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【入手方法】Myocardial protection by methylprednisolone sodium succinate during the reperfusion period after cardioplegic arrest in pig hearts.
To assess the efficacy of methylprednisolone sodium succinate (MPSS), an immunosuppressant, as a cardioprotective agent, we compared the efficacy of MPSS in 8 pigs subjected to cardioplegic arrest (CP) for aortic cross-clamping and reperfusion (CP+R) and in a second group of 8 pigs subjected to CP+R with subsequent myocardial recovery and left ventricular function, without any treatment, after release of CP (CP+R+). Hemodynamics, intracardiac pressures, and left ventricular function were evaluated before and after CP. Eight pigs were used as controls. The infusion of MPSS during reperfusion (3 mg/kg/hr) improved the recovery of left ventricular function and decreased left ventricular end-diastolic pressure after CP. In the control group, left ventricular end-diastolic pressure was unchanged by CP (10.1 +/- 2.7 vs 10.3 +/- 4.3 mm Hg). In the MPSS group, it was improved after CP (7.2 +/- 1.4 vs 15.4 +/- 2.4 mm Hg). Left ventricular end-diastolic pressure was significantly reduced by CP+R+ in both the control and MPSS groups. In contrast, left ventricular end-diastolic pressure during reperfusion was significantly higher in the control group than in the MPSS group (14.5 +/- 3.2 vs 8.9 +/- 2.8 mm Hg; p Category: Creative Development
A project in progress: Over the past few months I’ve been working on improving some of my existing game assets as well as recreating a few entirely new levels.
The scale of the levels will be significantly larger, and I’ll also be implementing some new methods of levelling that don’t involve simply adding more rooms. For example, I’ll be creating secret rooms that are accessible only once a certain set of requirements have been met.
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Minimum System Requirements:
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Please consider using the latest software version if you are experiencing any difficulty playing this game.
The full PC version of Forgotten Planet is supported on the following operating systems: